Real-Time Statistical Speech Translation

This research investigates the Statistical Machine Translation approaches to translate speech in real time automatically. Such systems can be used in a pipeline with speech recognition and synthesis software in order to produce a real-time voice communication system between foreigners. We obtained three main data sets from spoken proceedings that represent three different types of human speech. TED, Europarl, and OPUS parallel text corpora were used as the basis for training of language models, for developmental tuning and testing of the translation system. We also conducted experiments involving part of speech tagging, compound splitting, linear language model interpolation, TrueCasing and morphosyntactic analysis. We evaluated the effects of variety of data preparations on the translation results using the BLEU, NIST, METEOR and TER metrics and tried to give answer which metric is most suitable for PL-EN language pair.Comment: machine translation, polish englis

Simple model of bouncing ball dynamics: displacement of the table assumed as quadratic function of time

Nonlinear dynamics of a bouncing ball moving in gravitational field and colliding with a moving limiter is considered. Displacement of the limiter is a quadratic function of time. Several dynamical modes, such as fixed points, 2 - cycles and chaotic bands are studied analytically and numerically. It is shown that chaotic bands appear due to homoclinic structures created from unstable 2 - cycles in a corner-type bifurcation.Comment: 11 pages, 6 figure

Simple model of bouncing ball dynamics. Displacement of the limiter assumed as a cubic function of time

Nonlinear dynamics of a bouncing ball moving vertically in a gravitational field and colliding with a moving limiter is considered and the Poincare map, describing evolution from an impact to the next impact, is described. Displacement of the limiter is assumed as periodic, cubic function of time. Due to simplicity of this function analytical computations are possible. Several dynamical modes, such as fixed points, 2 - cycles and chaotic bands are studied analytically and numerically. It is shown that chaotic bands are created from fixed points after first period doubling in a corner-type bifurcation. Equation for the time of the next impact is solved exactly for the case of two subsequent impacts occurring in the same period of limiter's motion making analysis of chattering possible.Comment: 8 pages, 1 figure, presented at the DSTA 2011 conference, Lodz, Polan

Triple immunofluorescence labeling of atherosclerotic plaque components in apoE/LDLR -/- mice.

This paper presents a simple and reliable method of triple immunofluorescence staining that allows simultaneous detection of various cell types present in atherosclerotic plaque of apolipoprotein E and LDL receptor-double knockout (apoE/LDLR -/-) mice. We used combined direct and indirect procedures applying commercially available primary antibodies raised in different species to detect smooth muscle cells (Cy3-conjugated mouse anti-smooth muscle actin, SMA), macrophages (rat anti-CD68) and T lymphocytes (rabbit anti-CD3). Fixation of the material in acetone and modified incubation protocol employing nonfat dry milk in preincubation and incubation media significantly increased the intensity of labeling and effectively quenched the background. Our method offers an efficient way to detect qualitative as well as quantitative changes of macrophages, T lymphocytes and smooth muscle cells in atherosclerotic plaque of apoE/LDLR -/- mice during atherosclerosis development or in response to pharmacological treatment

A Search for High-Frequency Coronal Brightness Variations in the 21 August 2017 Total Solar Eclipse

We report on a search for short-period intensity variations in the green-line FeXIV 530.3 nm emission from the solar corona during the 21 August 2017 total eclipse viewed from Idaho in the United States. Our experiment was performed with a much more sensitive detection system, and with better spatial resolution, than on previous occasions (1999 and 2001 eclipses), allowing fine details of quiet coronal loops and an active-region loop system to be seen. A guided 200-mm-aperture Schmidt-Cassegrain telescope was used with a state-of-the-art CCD camera having 16-bit intensity discrimination and a field-of-view 0.43 degree x 0.43 degree that encompassed approximately one third of the visible corona. The camera pixel size was 1.55 arcseconds, while the seeing during the eclipse enabled features of approx. 2 arcseconds (1450 km on the Sun) to be resolved. A total of 429 images were recorded during a 122.9 second portion of the totality at a frame rate of 3.49 images per second. In the analysis, we searched particularly for short-period intensity oscillations and travelling waves, since theory predicts fast-mode magneto-hydrodynamic (MHD) waves with short periods may be important in quiet coronal and active-region heating. Allowing first for various instrumental and photometric effects, we used a wavelet technique to search for periodicities in some 404 000 pixels in the frequency range 0.5-1.6 Hz (periods: 2 second to 0.6 second). We also searched for travelling waves along some 65 coronal structures. However, we found no statistically significant evidence in either. This negative result considerably refines the limit that we obtained from our previous analyses, and it indicates that future searches for short-period coronal waves may be better directed towards Doppler shifts as well as intensity oscillations

A phase II dose-ranging study of mirabegron in patients with overactive bladder

Introduction and hypothesis Mirabegron is a potent and selective β3-adrenoceptor agonist that may represent an alternative treatment option in place of antimuscarinics for patients with overactive bladder. Methods Patients completed a single-blinded, 2-week placebo run-in period followed by 12 weeks of randomized (n=928) double-blinded treatment with mirabegron oral controlled absorption system (OCAS) 25, 50, 100, or 200 mg once-daily (QD), placebo or tolterodine extended release (ER) 4 mg QD. The primary endpoint was change from baseline to end-of-treatment in mean number of micturition episodes/24 h. Secondary endpoints included changes in mean volume voided per micturition; mean number of urinary incontinence, urgency urinary incontinence, and urgency episodes/24 h; severity of urgency; nocturia; and quality of life measures. Safety parameters included vital signs, adverse events, laboratory tests, electrocardiogram measurements and post-void residual volume. Results Mirabegron 25, 50, 100, and 200 mg resulted in dosedependent reductions (improvements) from baseline to end-oftreatment in micturition frequency of 1.9, 2.1, 2.1, and 2.2 micturitions/24 h respectively, versus 1.4 micturitions/24 h with placebo (p≤0.05 for the mirabegron 50-, 100-, and 200-mg comparisons). There was a statistically significant improvement with mirabegron compared with placebo for most secondary endpoints including quality of life variables. While there was a significant (p<0.05) increase from baseline in pulse rate in the mirabegron 100-mg and 200-mg groups, this was not associated with an increased incidence of cardiovascular adverse events. Conclusions The favorable efficacy and tolerability of mirabegron in this phase II dose-finding study has led to its successful advancement into a phase III clinical development program

A quick approach for rheological evaluation of warm asphalt binders using response surface method

This paper describes a quick approach for quantification of the effects of a chemical warm named Rediset, and its interactions with temperature and aging on the rheological properties of asphalt binders using Response Sur-face Method. The central composite method was applied to design experimental programs for three test temperature conditions, namely; very high temperature (120–180 °C), high temperature (46–82 °C), and intermediate temperature (19–31 °C). Rotational viscosity, G*/sin δ and G*sin δ were selected as parameters to assess the effects of the chemical warm additive on the rheological properties of asphalt binders for different aging conditions. Evaluation of the effects of this additive on the transformed value of G*/sin δ at high temperatures indicates that additive content has significant effect on Ln(G*/sin δ). The results for intermediate temperatures show that this additive has a positive effect on G*sin δ of asphalt binders